6. Masterclass With Masterjohn: Energy Metabolism
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Introduction
1. Welcome
1. Thermodynamics, Energy, and Order
2. Activation Energy and Enzymes
3. Cellular Respiration
4. Aconitase, ROS, and the Abilities of the Electron Transport Chain
5. Isocitrate & α-Ketoglutarate Dehydrogenases, AMPK, and the Need for ATP
6. How Isocitrate Dehydrogenase Makes Oxalosuccinate Decarboxylate Itself
7. α-Ketoglutarate Dehydrogenase: A Massive Enzymatic Factory
8. 7 Unforgettable Things About α-Ketoglutarate Dehydrogenase
9. Why Does CoA Come Back to the TCA Cycle?
10. That Moment You Rip Apart Water to Get Your Oxygen
11. How to Interpret Urinary Tests of TCA Cycle Intermediates
12. Carbs, Fat, and Carbon Dioxide
13. Pyruvate Dehydrogenase: Why Carbs Leave Your Thiamin Working Overtime
14. Thiamin, Carbs, Ketogenic Diets, and Microbes
15. Lactate: Rescuing NAD+ and Generating ATP From Glycolysis
16. Anaplerosis: Why Carbs Spare Protein in Ways That Fat Can’t
17. Carbs and Sports Performance: The Principles
18. Carbs and Sports Performance: The Evidence
19. Glycolysis: The Miracle of Turning Phosphate Into Water
20. Beta-Oxidation: When Fat and Water Mix
21. What Shuts Down Glycolysis? Too Much Energy.
22. What Shuts Down Fat Burning? Too Much Energy.
23. Is Insulin Really a Response to Carbohydrate or Just a Gauge of Energy Status?
24. How Insulin Makes You Burn Carbs for Energy
25. How Insulin Stops Fat-Burning
26. Why Insulin Doesn’t Make Us Fat
27. The Pentose Phosphate Pathway: The Many Essential Roles of Glucose
28. Insulin as a Gauge of Short-Term Energy Supply and Energetic Versatility
29. Gluconeogenesis: Expensive, but Essential
30. Gluconeogenesis Occurs When the Liver is Rich in Energy and the Body is Deprived of Glucose
31. Gluconeogenesis as a Stress Response: Regulation by Cortisol
32. This is How Ketogenesis Works
33. This is How We Burn Ketones for Energy
34. This is Why We Make Ketones
35. Ketone Homeostasis During Fasting
36. Ketoacidosis: The Dark Side of Ketones
37. Inuit Genetics Show Us Why Evolution Does Not Want Us In Constant Ketosis
38. The Origins of the Ketogenic Diet: Epilepsy
39. How Neurons Get Excited

Introduction

1 Lesson