6. Masterclass With Masterjohn: Energy Metabolism
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Introduction

Welcome
1. Thermodynamics, Energy, and Order

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2. Activation Energy and Enzymes

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3. Cellular Respiration

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4. Aconitase, ROS, and the Abilities of the Electron Transport Chain

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5. Isocitrate & α-Ketoglutarate Dehydrogenases, AMPK, and the Need for ATP

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6. How Isocitrate Dehydrogenase Makes Oxalosuccinate Decarboxylate Itself

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7. α-Ketoglutarate Dehydrogenase: A Massive Enzymatic Factory

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8. 7 Unforgettable Things About α-Ketoglutarate Dehydrogenase

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9. Why Does CoA Come Back to the TCA Cycle?

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10. That Moment You Rip Apart Water to Get Your Oxygen

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11. How to Interpret Urinary Tests of TCA Cycle Intermediates

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12. Carbs, Fat, and Carbon Dioxide

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13. Pyruvate Dehydrogenase: Why Carbs Leave Your Thiamin Working Overtime

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14. Thiamin, Carbs, Ketogenic Diets, and Microbes

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15. Lactate: Rescuing NAD+ and Generating ATP From Glycolysis

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16. Anaplerosis: Why Carbs Spare Protein in Ways That Fat Can’t

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17. Carbs and Sports Performance: The Principles

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18. Carbs and Sports Performance: The Evidence

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19. Glycolysis: The Miracle of Turning Phosphate Into Water

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20. Beta-Oxidation: When Fat and Water Mix

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21. What Shuts Down Glycolysis? Too Much Energy.

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22. What Shuts Down Fat Burning? Too Much Energy.

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23. Is Insulin Really a Response to Carbohydrate or Just a Gauge of Energy Status?

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24. How Insulin Makes You Burn Carbs for Energy

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25. How Insulin Stops Fat-Burning

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26. Why Insulin Doesn’t Make Us Fat

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27. The Pentose Phosphate Pathway: The Many Essential Roles of Glucose

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28. Insulin as a Gauge of Short-Term Energy Supply and Energetic Versatility

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29. Gluconeogenesis: Expensive, but Essential

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30. Gluconeogenesis Occurs When the Liver is Rich in Energy and the Body is Deprived of Glucose

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31. Gluconeogenesis as a Stress Response: Regulation by Cortisol

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32. This is How Ketogenesis Works

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33. This is How We Burn Ketones for Energy

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34. This is Why We Make Ketones

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35. Ketone Homeostasis During Fasting

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36. Ketoacidosis: The Dark Side of Ketones

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37. Inuit Genetics Show Us Why Evolution Does Not Want Us In Constant Ketosis

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38. The Origins of the Ketogenic Diet: Epilepsy

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39. How Neurons Get Excited

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15. Lactate: Rescuing NAD+ and Generating ATP From Glycolysis