Many people use niacin supplements to reduce their methylation rate. Some use it regularly because they are “overmethylators” and some use it intermittently when they experience symptoms they associate with overmethylation.

In this episode, I describe why I don’t recommend using niacin in this way. Doing so is using niacin as a drug, not a nutrient. Our goal should be instead to supply glycine in nutritionally adequate amounts to make the methylation system run smoothly like a well-oiled machine.

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